At Villa Pliniana, lavish, 16th-century architecture has been brought to the present day by Patricia Urquiola, making for a charming lakeside getaway. Under the care of Sereno Hotels, the estate’s recent restoration ensured the preservation of original design details throughout, like Venetian terrazzo flooring, detailed ceiling murals, and fireplaces. Today, it’s updated with fresh, clean furnishings and indoor greenery—seen throughout the villa’s 17 bedrooms and three standalone villas, which can accommodate up to 39 guests. The estate’s expansive grounds also include amenities like two ballrooms, a pool, a spa, Turkish baths, Scottish showers, a sauna, a heliport, and a jetty.